The 'perfect' dose.

When taking CBD it is particularly important to identify an appropriate dose - This will optimise your chances of experiencing the therapeutic properties while avoiding any potential side effects.

Everyone responds differently to Cannabidiol (CBD) so it may require a little 'trial and error' before your see results. In this article we discuss some factors to take into account when finding the right dose for you.

For those of you that are new to CBD & Hemp extracts, please feel free to visit our FAQ page or news & information section to learn more. 



There are many factors that can influence our bodies response to CBD such as:

- Strength or percentage (CBD content of the product you are taking.)

- Type of CBD product (Oil drops, capsules ect)

- Structure of active ingredients (Liposomal , Water soluble CBD ect)

- Methods of administration (Sublingual absorption, Vaping ect )

- Physical Characteristics (Body weight, Age & General health.)

- Reasons for taking CBD (Such as a medical condition.)

- Body chemistry (The ways in which our bodies react to particular chemicals.)

As we mentioned earlier, everyone is different, so some of these factors may or may not effect your experience with CBD. 


Endocannabinoid receptors around the body

Body weight:

This is the process of estimating an appropriate dose based on your weight. In this case, most people would recommend taking between 1 & 5 mg per every 5kg of body weight.

For example an 11 stone person (approx 70kg) would take between 14 & 70 mg of CBD per day.

As you can see, the range is pretty vast making this method particularly inaccurate. It is also important to bare in mind that it does not take into account what you are using CBD for. Most importantly, this method introduces fairly high doses of CBD into the system which could shock your Endocannabinoid system, resulting in potential side effects. 

However, do note that CBD is considered safe to take on a regular basis with no reports of overdose. 

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Start low, Go slow:

Regardless of what you are taking CBD for, we would always recommend starting on a low dose & gradually increasing it each week until you see results.

A good place to start is between 5 & 15 milligrams per day.

With this method it is important to monitor how your body reacts to each dose on a weekly basis to avoid taking more than necessary. Once you are happy with the effects of a particular dose, continue to use that as a guideline for any other products you use.

In particular circumstances however, users may benefit from taking a larger dose from the start.


CBD oil uk


Bio-availability of CBD:

In short, Bio-availability is the degree & rate in which a substance is absorbed into the blood stream - Generally speaking, the greater the Bio-Availability the more is successfully absorbed.

Increasingly so, manufacturers are beginning to use certain processes to improve the way our bodies utilise the active chemicals found in Hemp & Cannabis Oils.  

Below we will discuss the Bio-Availability of the 2 most common forms of CBD Oil: 

Traditional CBD Oil - These types of Oils are usually made from refined Hemp extract diluted in a carrier Oil (Often Hemp seed or MCT Oil). When these Oils are consumed Orally, a process called 'First pass metabolism' takes place. During this process, CBD is metabolised by the liver, lungs, gastrointestinal tract and blood. This process causes a significant reduction in the amount of CBD that will finally enter your bloodstream with the rest being stored in fatty cells. Bio-availability varies between 6 & 13 percent. Consequently, people often have to consume excessive amounts to experience the desired effects.  

Liposomal CBD Oil - Liposomes are essentially molecular fat bubbles that have been used for decades as highly effective drug delivery systems. They encapsulate the active chemicals and deliver them directly to cells, tissue, and organs all throughout the body. Bio-availability is believed to be approximately 20%. Aside from delivering higher concentrations of CBD in general, Liposomes allow individuals to use less CBD while achieving the same effects.


Liposome CBD uk


Biphasic action of CBD:

In simple terms, 'Biphasic action' refers to the opposing effects a substance has at low doses compared to high doses - Studies suggest that smaller amounts of CBD (15mg) can increase alertness & focus while larger amounts (50mg+) cause a more sedating effect.

This should be considered when taking any form on CBD.



In truth, there is no 'Perfect' dose of CBD - Everyone reacts differently to specific compounds so it is pretty difficult to state exactly what dose is appropriate before trying it. 

Hopefully, by taking all these things into consideration, you are able to incorporate CBD into your lifestyle in an efficient and effective way. 


*Always consult a healthcare professional prior to consuming any form of CBD. All products available at cannabidolpharm.com are not intended to treat or cure any medical conditions.


If your have any questions please feel free to contact us :) We'd be happy to help!